Less than 50% of pregnancies in women with lupus have complications, but all lupus pregnancies are considered high-risk. Lupus can complicate pregnancy with an increased risk of miscarriage, premature delivery, and preeclampsia, as well as heart problems in the baby. Hydroxychloroquine yellow skin Typical plaquenil maculopathy oct Recent reports have highlighted that chloroquine CQ is capable of inhibiting ZIKV endocytosis in brain cells. We applied pharmacokinetic modeling to develop a predictive model for CQ exposure to identify an optimal maternal/fetal dosing regimen to prevent ZIKV endocytosis in brain cells. According to the Centers for Disease Control and Prevention CDC, chloroquine is considered safe to use during pregnancy. Tell your doctor if you're pregnant or might become pregnant while taking. Taking chloroquine during pregnancy is not expected to cause any problems that would require extra monitoring of your baby. However, if you have had malaria during your pregnancy your doctor may wish to monitor your pregnancy more closely. Are there any risks to my baby if the father has taken chloroquine? “Preconception counseling allows women who have lupus to discuss their personal health with their doctor to assess risks based on how lupus has affected her thus far,” says Larry Matsumoto, MD, maternal fetal specialist at Atlanta Perinatal Consultants. If you have lupus and are considering having a baby, consider these tips to ensure a safe pregnancy and healthy baby. Chloroquine during pregnancy Hydroxychloroquine DermNet NZ, Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs Plaquenil getting immuneChloroquine for yeastPlaquenil drug action Alternative drugs to chloroquine are required to prevent the deleterious effects of malaria in pregnancy. Fear of potential toxicity has limited antimalarial drug use in pregnancy. Animal toxicity studies have documented teratogenicity when antimalarials are administered at high dosages. The Safety of Antimalarial Drugs in Pregnancy SpringerLink. Bumps - best use of medicine in pregnancy. Azithromycin-chloroquine and the intermittent preventive.. Pregnancy and Chloroquine According to the Centers for Disease Control and Prevention CDC, chloroquine is considered safe to use during pregnancy. Tell your doctor if you're pregnant or might. Primaquine is contraindicated in pregnancy due to the risk of severe haemolysis in glucose-6-phosphate dehydrogenase G6PD deficient individuals. Pregnant women may require suppressive treatment, usually with chloroquine, until delivery. Background/Purpose Chloroquine CQ and Hydroxychloroquine HCQ have been used for years during pregnancy for multiple indications malaria prevention, autoimmune disorders, etc. Recently, some countries face restrictions to prescribe these drugs during pregnancy, due to report of ocular toxicity in animal models and potential genotoxicity.