I was told I didn't have to taper it like prednisone, and that I shouldn't expect any rebound type of reaction like you get when your body adjusts to being off pred. But everyone is taking a different mix of drugs and maybe you're taking something I don't that would make your doctor's recommendation for you different. Chloroquine is used for Chloroquine phosphate bp Can I stop taking anti-malarials suddenly? Long-term anti-malarial use is normally safe. However, if you stop taking your anti-malarial drugs, you may experience a lupus flare. Potential added benefits of anti-malarial drugs. Anti-malarial drugs may have additional health benefits for some people. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your. Again, I was surprised at how much relief I was getting and I noticed it almost immediately. The first time I did it was about 6 months after starting it because I didn't think it was doing anything for me. Turns out that the benefits come on so slowly that I didn't realize it was helping. Second time was maybe a year or so ago when I thought maybe I was getting a little better - and because of potential eye effects I thought I should try to eliminate it if possible. Abruptly stopping plaquenil Discontinued Plaquenil.itching skin?, Stopping plaquenil. DailyStrength Retinal toxicity hydroxychloroquine I had to stop Plaquenil after a few days. I couldn't walk, was dizzy, my speech was slurred, blurry vision, etc. but, I'm the one who usually gets side effects. I know people who Plaquenil has worked wonders. The side effects cleared up within a week. I also have Sjorgens, and my eyes were dryer on Plaquenil, but the blurry vision was the worst. Stopping Plaquenil? DailyStrength. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. I would assume from this that people had sudden and quite severe flares when stopping the plaquenil. There is always the chance that some people might interpret this as withdrawal, but I think it is probably always in the eye of the beholder. Hard to determine what other people are going through and not worth seeing who it right or wrong.