Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and eye pain Side effectsof chloroquine Plaquenil Hydroxychloroquine sulfate is a drug originally used to prevent or treat malaria. Malaria is a serious but rare disease caused by bites from infected mosquitos. Now the drug is used to treat inflammatory diseases. This type of disease occurs when the body's immune system attacks its own healthy tissue. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Rheumatic disease. It's common for people who have Sjogren's syndrome to also have a rheumatic disease — such as rheumatoid arthritis or lupus. Complications. The most common complications of Sjogren's syndrome involve your eyes and mouth. Dental cavities. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil related diseases Lichen planopilaris Genetic and Rare Diseases., Plaquenil Oral Uses, Side Effects, Interactions. Does plaquenil cause nerve pain Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Sjogren's syndrome - Symptoms and causes - Mayo Clinic. Lupus Overlap Diseases What are Common Diseases.. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. CONDITIONS OF USE The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover. In a US study of 2.900 patients with rheumatic diseases, no one was blinded by hydroxychlorokine Plaquenil Among 31 X% who had been diagnosed with blindness or toxic maculopathy, 1% had high blood pressure, 70% kidney failure and 60% cataract cataracts, which may explain reduced vision.