This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Chloroquine phosphate usp Plaquenil leg pain Chloroquine mode of mechanism action Objectives Suicidal and accidental poisoning due to drug overdose is one of the common reason of morbidity and mortality all over the world. Considering such statement, toxicological analysis becomes imperative in suicidal, accidental and also in homicidal deaths now-a-days. Chloroquine poisoning, on the other hand, is well understood due to its widespread use in parts of Asia, Africa and Europe for inducing abortion and attempting suicide.6 9 Animal studies have shown the toxicity profile of chloroquine to be approximately two to three times that of hydroxychloroquine.7 Moreover, fatality rates for chloroquine. Don Michael TA, Aiwazzadeh S. The effects of acute chloroquine poisoning with special reference to the heart. Am Heart J. 1970 Jun; 79 6831–842. Gustafsson LL, Walker O, Alván G, Beermann B, Estevez F, Gleisner L, Lindström B, Sjöqvist F. Disposition of chloroquine in man after single intravenous and oral doses. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine overdose fatal Chloroquine PeaceHealth, Accidental hydroxychloroquine overdose resulting in. 200 mg of plaquenil how long to workIs generic plaquenil as good Hydroxychloroquine overdose is a rare condition and often results in severe cardiovascular toxicities. We report 2 cases of fatal hydroxychloroquine overdose 1 patient had co-ingestion of. A Case of Fatal Hydroxychloroquine Overdose. Chloroquine poisoning. Rapidly fatal without treatment.. Chapter 51. Chloroquine and Other Aminoquinolines Poisoning & Drug.. Overdose. Chloroquine is very dangerous in overdose. It is rapidly absorbed from the gut. In 1961, published studies showed three children who took overdoses died within 2.5 hours of taking the drug. While the amount of the overdose was not cited, the therapeutic index for chloroquine is known to be small. A case of fatal hydroxychloroquine overdose HT Fung, KK Lam, OF Wong, B Lau, CW Kam A 28-year-old woman ingested 20 g of hydroxychloroquine sulphate for suicidal attempt. She developed hypotension, cardiac conduction disturbance, hypokalemia and hypoglycemia. Despite treatment with An overdose of chloroquine can be fatal, especially in children. Chloroquine overdose must be treated quickly. You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose.