Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine selleckchem Plaquenil and ibuprofen together Icd 10 code for plaquenil use The sulfate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine sulfate Plaquenil hydroxychloroquine sulfate dosing, indications., Chloroquine - Wikipedia Plaquenil to treat psoriasisPlaquenil cut in half Chloroquine sulfate European Pharmacopoeia EP Reference Standard Synonym Chloroquine sulfate monohydrate CAS Number 6823-83-2. Empirical Formula Hill Notation C 18 H 28 ClN 3 O 4 S H 2 O. Molecular Weight 435.97. NACRES NA.24 Chloroquine sulfate European Pharmacopoeia EP Reference.. Hydroxychloroquine SULFATE -. Chloroquine sulfate C18H28ClN3O4S - PubChem. Chloroquine sulfate United States Pharmacopeia USP Reference Standard Synonym Chloroquine sulfate monohydrate CAS Number 6823-83-2. Empirical Formula Hill Notation C 18 H 28 ClN 3 O 4 S H 2 O. Molecular Weight 435.97. NACRES NA.24 Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine Aralen and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Malarial parasites invade human red blood cells. The study suggested that chloroquine may prevent internalization by inhibiting toxin binding at the cell membrane or inhibit lysosomal processing of the toxin in the cell interior. Hydroxychloroquine, a related quinoline agent, may also interfere with the actions of botulinum toxins.