PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Plaquenil cardiac side effects Hydroxychloroquine plaquenil side effects Fever with hydroxychloroquine Spectral-domain optical coherence tomography in hydroxychloroquine retinopathy Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Jun 13, 2016 Irreversible retinal damage has been observed in some patients who had received long-term or high-dosage 4-aminoquinoline therapy for discoid and systemic lupus erythematosus, or rheumatoid arthritis. After these drugs were abandoned for the treatment of malaria, more study was done, and they were found to be effective for discoid lupus, subacute cutaneous lupus, dermatomyositis, rheumatoid arthritis, and psoriatic arthritis. Plaquenil has a better safety profile than chloroquine and is most commonly used today. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Plaquenil and discoid lupus dosage Drug spotlight on hydroxychloroquine Lupus Foundation of., DailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet Hydroxychloroquine when to takePlaquenil is for I take 200mg Plaq per day and it nips all my pain in the bud. however, some side effects of Lupus I have are Lupus Fog, smelling non existent odors acrid smells, occasional dizziness. Other than these, my life is fairly normal. Lupus & Plaquenil/Pain -. Plaquenil Use in Autoimmune Diseases. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil is sold in 200mg tablets. The recommended adult dosage for a person with lupus is 200 to 400 mg daily. It can be taken in two doses or at one time. Doses above 400 mg/day are not recommended. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Regarding hydroxychloroquine levels and lupus activity, Costedoat- Chalumeau et al measured whole blood levels in 143 individuals taking a standard dose of 400 mg per day and found a lower hydroxychloroquine level in those with active disease and that lower baseline levels were predictive of disease flare.