Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Chloroquine action and target Hydroxychloroquine and notalgia paresthetica Chloroquine related chloroform Mar 01, 2011 On examination, best-corrected visual acuity was 20/50 in each eye. Slit-lamp examination was significant for mild to moderate cataract in each eye. Dilated fundus examination was notable for only mild bilateral macular pigment alterations Figures 1-2. Humphrey visual field 10-2 evaluation revealed dense bilateral central scotomas Figures 3-4. By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr. Macular Society Eye screening for patients taking hydroxychloroquine At this appointment, a number of photographs and scans will be taken of your retina to assess your eye health and your suitability for screening. Not all patients can use the equipment needed for screening, such as people with advanced dementia or Parkinson’s disease. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil eye exam standard of care User Reviews for Plaquenil to treat Lyme Disease. -, Rx Side Effects New Plaquenil Guidelines and More - American Academy. Chloroquine phosphate 250 mg oral tabletPrimaquine chloroquine dosageDo you need a baseline eye exam before taking hydroxychloroquineChloroquine phosphate 250 mg malariaHydroxychloroquine and tinnitus Multifocal Electroretinopathy measures electrical responses of various cell types in the retina. It is thought that although the bull’s eye seen on ophthalmic exam represents a disruption of the pigmented part of the retina, it is the photoreceptors that are the targets of hydroxychloroquine toxicity. My Take on New Ocular Screening Guidelines for Plaquenil.. Eye screening for patients taking hydroxychloroquine.. Plaquenil Toxicity - Symptoms, Treatment, Risk Factors.. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. The risk is much higher in patients who have been taking the drug for 20 years or more. In these patients between 20 and 50 out of 100 will develop retinopathy. At this appointment, a number of photographs and scans will be taken of your retina to assess your eye health and your suitability for screening. Sep 23, 2015 As optometrists, it is important that we are aware of the possible ocular complications that can occur from the use of high risk medications. Patients starting chloroquine CQ or hydroxychloroquine HCQ; i.e. Plaquenil should have a baseline examination that serves as a reference point, as well as to rule out any preexisting maculopathies.