Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. Chloroquine has not been formally assigned to a pregnancy category by the FDA. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm. Plaquenil and kidney disease Plaquenil pap frequency Does plaquenil reduce fevers Pregnancy and Chloroquine According to the Centers for Disease Control and Prevention CDC, chloroquine is considered safe to use during pregnancy. Tell your doctor if you're pregnant or might. Despite these risks, corticosteroids are considered relatively safe throughout pregnancy when given at low doses below 15 mg/day. They should be avoided, if possible, during the first trimester, when risk for defects of the hard palate are highest. A pregnancy lasts for about 40 weeks. The weeks are grouped into three trimesters. The first trimester is the time in between fertilization of the egg by the sperm conception and week 12 of a. Chloroquine should only be given during pregnancy when need has been clearly established. Chloroquine is the drug of choice for the prophylaxis and treatment of sensitive malaria species during pregnancy. Is chloroquine safe in first trimester of pregnancy Chloroquine Use During Pregnancy, Drug Safety in Pregnant & Nursing Women Does plaquenil give you brittle bonesHow to make chloroquine poison A cohort of 169 births to women who were exposed throughout pregnancy to chloroquine 300 mg base once a week for chemosuppression of malaria was studied. PDF Safety of chloroquine in chemosupression of malaria.. The First Trimester of Pregnancy. Malaria during pregnancy New study assesses risks during.. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 In the first trimester of pregnancy, 67 45.6% of the GPs prescribed quinine for their patients who presented with acute malaria attack, while 60 40.8% prescribed chloroquine. Other anti-malaria drugs prescribed in the first trimester for acute treatment of malaria infection were as shown in Table 2. Alternative drugs to chloroquine are required to prevent the deleterious effects of malaria in pregnancy. Fear of potential toxicity has limited antimalarial drug use in pregnancy. Animal toxicity studies have documented teratogenicity when antimalarials are administered at high dosages.