Plaquenil dose based on weight

Discussion in 'Canada Pharmacy' started by Lancelot, 05-Mar-2020.

  1. SilverX Well-Known Member

    Plaquenil dose based on weight


    If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female.

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    The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. For malaria prevention, take this medication by mouth once a week on the same day of the week, or as directed by your doctor. Mark a calendar to help you remember. The plaquenil has caused a weight gain of about 20-25 pounds for me. Since I was diagnosed with MCTD a year ago, Plaquenil has been the only medication besides eye supplements, thyroid meds - been stable for years, and most recently Evoxac that I have been given. A daily dose of 6.5mg/kg ideal body weight places patients at higher risk, but a daily dose below this level did not preclude the patient from developing toxicity after many years of treatment. A cumulative dose of 1000g of hydroxychloroquine or 460g of chloroquine was likely the largest risk factor, which was typically achieved after 5-7.

    For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day.

    Plaquenil dose based on weight

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  5. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. As one can see, the height that corresponds to an ideal body weight of 135 pounds varies across the formulas.

    • Ideal Body Weight for Calculating Hydroxychloroquine Dosage..
    • Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening.
    • PATIENT FACT SHEET Hydroxychloroquine Plaquenil.

    The dosage is based on body weight. 6.5 mg/kg maximum dose 400 mg should be given on the same day each week starting 2 weeks before exposure to malaria. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy.

     
  6. portek Guest

    that prescribed it I am no longer seeing and wont re-fill it and I dont see my new Rheum. When it is gone she said I can resume at my own pace. Taking Plaquenil for Rheumatoid Arthritis If you've stopped taking plaquenil, did you start getting. Had to stop taking Plaquenil -
     
  7. MIB Guest

    Plaquenil and weight loss DailyStrength I recently went on Plaquenil a few months ago, and I have been noticing how much weight I've been losing. I feel like I am losing too much weight. I am a thin person, and I am sick very often. Last week, I lost three pounds, and the week before I lost two pounds. Everyone keeps commenting that I'm.

    Plaquenil & Weight Gain/Loss -
     
  8. YuraZ User

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus