Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Synthesis of chloroquine from 4 7-dichloroquinoline Hydroxychloroquine 200 mg para que sirve I've been on Plaquenil 200mg 2 x day for 6 days and I am so tired. Slept 11 hours last night and I am still tired. Diagnosed with Psoriatic or Rheumitoid Arthritis Dr. not sure yet. I didn't have significant fatigue previously, so I assume it's the medicine. I also had a steriod shot in swollen joint, but I don't think that would cause fatique. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine tiredness Evaluations from Patients who take Hydroxychloroquine., Hydroxychloroquine Uses, Dosage & Side Effects - Buy chloroquine plus proguanil Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Hydroxychloroquine Side-effects, uses, time to work. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Will you have Fatigue with Plaquenil - eHealthMe. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue.