This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Chloroquine pregnancy Plaquenil erosive arthritis Chloroquine is a member of quinolone family and is a weak intercalating agent. Chloroquine is used for treating amebiasis, rheumatoid arthritis, discoid and systemic lupus erythematosus. Application DNA intercalator. Also used to increase transfection efficiency. Chloroquine diphosphate salt has been used • in in vitro antiplasmodial assays Chloroquine is a lysosomotropic agent that prevents endosomal acidification 1. It accumulates inside the acidic parts of the cell, including endosomes and lysosomes. This accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Chloroquine diphosphate salt, 98%, Acros Organics™ Click to view available options Quantity Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine diphospahe bbguy A place to buy Chloroquine REEF2REEF Saltwater and Reef., Chloroquine for research Cell-culture tested InvivoGen Chloroquine structure CONCLUSIONS Chloroquine diphosphate CDP is a helpful tool in the blood bank for two main applications. The most common application is to render direct antiglobulin test-positive red blood cells RBCs free from membrane-bound IgG; these treated RBCs can then be used for autologous adsorption and/or to determine the patient's RBC phenotype. Utility of chloroquine diphosphate in the blood bank laboratory.. Chloroquine diphosphate salt, 98%, Acros Organics Fisher.. Chloroquine diphosphate salt - Sigma-Aldrich. If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Uses Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live.