I would appreciate feedback on the reasoning outlined below. I have convinced myself that it makes sense, but am looking for independent feedback and have been struggling to get it. Puckering of tongue plaquenil Plaquenil vaginal Apr 02, 2019 Before using chloroquine for prophylaxis, it should be ascertained whether chloroquine is appropriate for use in the region to be visited by the traveler. Chloroquine should not be used for treatment of P. falciparum infections acquired in areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Blood Stage Prophylaxis In Vivax Malaria. Blood stage prophylaxis is the most common type of prophylaxis in use. Chloroquine, was the first drug in this group to be extensively used. It was introduced in the early 1950’s for the prevention of both falciparum and vivax malaria. Before using chloroquine for prophylaxis, it should be ascertained whether chloroquine is appropriate for use in the region to be visited by the traveler. Chloroquine should not be used for treatment of infections acquired in areas of chloroquine resistance or malaria occurring in patients where Chloroquine prophylaxis has failed. P. falciparum , etc.), or provide argument why this is a dumb idea. I would greatly appreciate it if someone could knit-pick this with a fine tooth comb and try and find some mistake I've made (off by a order of magnitude? When should prophylactic chloroquine be taken Chloroquine and Proguanil - Superdrug Health Clinic, Prophylaxis of Malaria - PubMed Central PMC Symptoms of retinal damage from plaquenilStopping plaquenil beforesurgery The steady-state serum concentration of 500mg of CQ taken once weekly is 0.1uM,12 which given the above reasoning, would be expected to lead to a lung concentration above the reported EC90 of SARS-CoV-2. 500mg of CQ taken once weekly is the malaria prophylaxis dose of CQ. This dose is extremely well-tolerated with minimal side-effects in most. COVID-19 Prophylaxis in Healthcare workers. - Health 2019. CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Jul 23, 2014 The standard treatment course should be completed and antimalarial chemoprophylaxis commenced one week after taking the first treatment dose, except in the case of mefloquine prophylaxis, which should be resumed at least twelve hours after the last treatment dose if quinine was used for standby treatment. Both adults and children should take one dose of chloroquine per week starting at least 1 week before traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. How should I take chloroquine? Follow all directions on your prescription label. Do not take chloroquine in larger or smaller amounts or for longer than recommended. To prevent malaria Start taking the medicine 2 weeks before entering an area where malaria is common. Chloroquine is usually taken once per week on the same day each week.