When should prophylactic chloroquine be taken

Discussion in 'Canadian Pharmacy Online' started by alexanderkum, 26-Feb-2020.

  1. gigabeam User

    When should prophylactic chloroquine be taken


    I would appreciate feedback on the reasoning outlined below. I have convinced myself that it makes sense, but am looking for independent feedback and have been struggling to get it.

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    Apr 02, 2019 Before using chloroquine for prophylaxis, it should be ascertained whether chloroquine is appropriate for use in the region to be visited by the traveler. Chloroquine should not be used for treatment of P. falciparum infections acquired in areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Blood Stage Prophylaxis In Vivax Malaria. Blood stage prophylaxis is the most common type of prophylaxis in use. Chloroquine, was the first drug in this group to be extensively used. It was introduced in the early 1950’s for the prevention of both falciparum and vivax malaria. Before using chloroquine for prophylaxis, it should be ascertained whether chloroquine is appropriate for use in the region to be visited by the traveler. Chloroquine should not be used for treatment of infections acquired in areas of chloroquine resistance or malaria occurring in patients where Chloroquine prophylaxis has failed. P. falciparum

    , etc.), or provide argument why this is a dumb idea. I would greatly appreciate it if someone could knit-pick this with a fine tooth comb and try and find some mistake I've made (off by a order of magnitude?

    When should prophylactic chloroquine be taken

    Chloroquine and Proguanil - Superdrug Health Clinic, Prophylaxis of Malaria - PubMed Central PMC

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  4. The steady-state serum concentration of 500mg of CQ taken once weekly is 0.1uM,12 which given the above reasoning, would be expected to lead to a lung concentration above the reported EC90 of SARS-CoV-2. 500mg of CQ taken once weekly is the malaria prophylaxis dose of CQ. This dose is extremely well-tolerated with minimal side-effects in most.

    • COVID-19 Prophylaxis in Healthcare workers. - Health 2019.
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    Jul 23, 2014 The standard treatment course should be completed and antimalarial chemoprophylaxis commenced one week after taking the first treatment dose, except in the case of mefloquine prophylaxis, which should be resumed at least twelve hours after the last treatment dose if quinine was used for standby treatment. Both adults and children should take one dose of chloroquine per week starting at least 1 week before traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. How should I take chloroquine? Follow all directions on your prescription label. Do not take chloroquine in larger or smaller amounts or for longer than recommended. To prevent malaria Start taking the medicine 2 weeks before entering an area where malaria is common. Chloroquine is usually taken once per week on the same day each week.

     
  5. WMG Moderator

    500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart. Aquarium Fish Chloroquine A "New" Drug for Treating Fish. Chloroquine Phosphate Aquarium Dosing Calculator. Chloroquine Phosphate - Fish Medication Information Coral.
     
  6. tati XenForo Moderator

    Multimodal Imaging in Plaquenil Toxicity Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is.

    Plaquenil Toxicity Screening - Retina Group of New York
     
  7. Buster62 Moderator

    HYDROXYCHLOROQUINE - Hydroxychloroquine sulfate Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolyl aminopentyl ethylamino ethanol sulfate 11. Hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration.

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.