Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What otc meds can be taken with plaquenil Plaquenil insert What is chloroquine base Mucocutaneous hyperpigmentation because of anti-malarial therapy has been reported since World War II 2; however, HCQ-associated hyperpigmentation seems to be less common than with other antimalarials such as chloroquine 3,4. Generally, dark color skin people have more melanin than light color skin people. When melanin forms deposit in the skin it causes pigmentation. There are two types of pigmentation Hyperpigmentation, and Hypopigmentation. Hyperpigmentation is a normal and harmless condition in which the skin becomes darker in color than the normal surrounding. Addison's disease can affect the skin and cause hyperpigmentation. Pictured is the hand of a person suffering from Addison's associated hyperpigmentation alongside the hand of a person who does not have the condition, but who comes from a similar ethnic background. An accident or illness can worsen the skin hyperpigmentation of Addison's disease. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine hyperpigmentation pictures face Melasma Chloasma - Pictures, Causes, Symptoms and Treatment., Skin Pigmentation Causes and Treatment Treating ra with plaquenilWhat is the difference between hydroxychloroquine and chloroquinePlaquenil and caffeineChloroquine malaria side effectsPlaquenil fights cancer Hyperpigmentation is a common skin condition, and there are a number of different treatment options available. Keep reading to learn more about your options, including products you can try at home. Hyperpigmentation Treatment Acids, Peels, Lasers, and More. Pictures of Skin Pigment Problems - Addison's Disease. Hyperpigmentation Treatments, Causes & Photos - RealSelf. Hyperpigmentation of the Skin Following Chloroquine Treatment 71 DISCUSSION AND CONCLUSION The aforesaid pigmentary changes of the skin al-though, could be explained by the underlying disorder or other concomitantly administered drug predniso-lone, have followed reasonable temporal sequence to Fig. 1 Clinical aspect of hyperpigmentation of hard palate induced by chloroquine therapy showing a blue-gray pigmented diffuse le-sion with irregular borders. with pressure. On extra-oral examination, pigmentation was not seen in the skin or in the ocular conjunctiva. Differential diagnosis included drug-induced hyperpig- Jul 11, 2017 Most of the symptoms of porphyria cutanea tarda appear on the skin. Common symptoms include blisters on skin that’s exposed to the sun, including the hands, face, and arms. photosensitivity, which means your skin is sensitive to the sun. thin or fragile skin. increased hair growth, usually on the face.