Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil antibiotic interactions Chloroquine pi3 kinase Chloroquine dna intercalation Estradiol plaquenil combination Hydroxychloroquine and the immune system. It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is. Hydroxychloroquine is contraindicated in patients with pre-existing maculopathy. Guidelines regarding the need for regular ophthalmological reviews vary. The American Academy of Ophthalmology recommends ophthalmological examination within the first year of treatment. Is not known. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. Activity in vitro and in Clinical Infections Hydroxychloroquine is active against the erythrocytic Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Hydroxychloroquine immunosuppressant Hydroxychloroquine Side-effects, uses, time to work, Long-term management of patients taking immunosuppressive. Chloroquine pretreatment degradation toxicity Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. It does not appear to be safe during Hydroxychloroquine - Wikipedia. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Is Hydroxychloroquine Plaquenil an Immunosuppressant.. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Immunosuppressive drugs, including cyclophosphamide and azathioprine, and adrenal hormones, such as prednisone PDS, are clinical drugs used in the treatment of LN 2,3. However, these drugs present significant side effects with long-term and high-dose application. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.