Additionally, another exception occurred while executing the custom error page for the first exception. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Z 038 is this hydroxychloroquine Plaquenil and myasthenia gravis The 10-2 white protocol is recommended as per AAO guidelines, although the red protocol may be more sensitive. Although perimetry is very dependent on patient engagement with the test, it may in some patients be the first modality to detect toxicity, even before mfERG 22, 42, 72 or SD-OCT. SD-OCT Peripheral retina was unremarkable OU. Fundus photos, visual field 10-2 were ordered as well as a spectral domain ocular coherence tomography SD-OCT see Figures 1-3. The appearance of disruption of the photoreceptor integrity line, perifoveal thinning, and paracentral scotomas confirmed a high likelihood of toxicity in this patient. The Risk of Retinal Toxicity with Plaquenil. The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. Plaquenil toxicity 10-2 Dr. Noskow's Case Report Plaquenil Toxicity - Hollywood., Determine risk for hydroxychloroquine retinal toxicity. Clarithromycin and hydroxychloroquine lymeMedicine plaquenil 200 mg Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Protecting your eyesight when taking Plaquenil Lupus.. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of Plaquenil hydroxychloroquine, if you use Plaquenil hydroxychloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if. A multitude of tests are needed to detect the earliest possible signs of hydroxychloroquine toxicity, according to Andrew A. Moshfeghi, MD, MBA. A traditional 10-2 test takes at least 15. Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is.