The clinical trials on this list are studying Hydroxychloroquine. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. Hydroxychloroquine sulfate and pregnancy Chloroquine preparation If you have any questions, contact a member of your healthcare team directly. If you're a patient at MSK and you need to reach a provider after pm, during the weekend, or on a holiday, call 212-639-2000. Studies in genetically engineered mouse models demonstrate that autophagy inhibition suppresses lung tumor development and progression, especially in Kras mutated tumors. We report safety and efficacy of adding an autophagy inhibitor, hydroxychloroquine HCQ to front-line platinum-based chemotherapy in a phase Ib single arm study in patients with metastatic NSCLC. Hydroxychloroquine and Gefitinib to Treat Lung Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Talk to your doctor for help in deciding if one is right for you. You may want to think about taking part in a clinical trial. Hydroxychloroquine and lung cancer A trial of chemotherapy and hydroxychloroquine for small., Modulation of autophagy with hydroxychloroquine in patients. Plaquenil dreams2 hydroxychloroquine sulfate plaquenil sulfate Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Hydroxychloroquine and Gefitinib to Treat Lung Cancer.. NCI Drug Dictionary - National Cancer Institute. Methotrexate is often the first treatment given to people with RA. But it could make you more likely to get some cancers, especially skin cancer. One study found methotrexate may be tied to melanoma, non-Hodgkin's lymphoma, and lung cancer. Hydroxychloroquine is a substance that decreases immune responses in the body. Palbociclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Estrogen can cause the growth of breast cancer cells. Drugs, such as letrozole, may lessen the amount of estrogen made by the body. Hydroxychloroquine HCQ, one of the classic anti-malarial drugs, has been used to treat cancer in several preclinical studies and clinical trials. Previous study suggested that HCQ was active in suppressing cell migration and metastasis, both in vitro and in vivo 4.