These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil what is Can you take hydroxychloroquine while breastfeeding Is coughing normal when taking plaquenil Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Keep away from children. Accidental exposure may cause death. If a child takes Plaquenil hydroxychloroquine by accident, get medical help right away. Use with care in children. Talk with the doctor. If you are 65 or older, use Plaquenil hydroxychloroquine with care. You could have more side effects. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil color vision effects Hydroxychloroquine Plaquenil Toxicity and., What Is Plaquenil? - American Academy of Ophthalmology Drug warnings for plaquenil Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Plaquenil Indications, Side Effects, Warnings -. Plaquenil Hydroxychloroquine Side Effects and Adverse.. Aug 30, 2011 Despite cessation of hydroxychloroquine, one-year follow-up revealed a mild worsening visual acuity to 20/30 OD and 20/25 OS, with new abnormalities on Amsler grid and deficits on color vision testing. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. This sort of retinal damage may result in patchy loss of central vision or patchy loss of vision just close to the centre of your vision. There are a number of other much less important side effects of Plaquenil, including changes in the cornea and changes in the eyelids.