One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. What does hydroxychloroquine look like Love plaquenil Is hydroxychloroquine used for fibromyalgia The new guidelines recommend 10-2 automated perimetry, plus at least one of SD-OCT, FAF, or mfERG if they are available. These tests should be performed at baseline and at each subsequent evaluation. Other tests may be considered as well, but are generally insufficiently sensitive to detect early evidence of hydroxychloroquine toxicity. Do you know the current screening recommendations for patients on Plaquenil? Which tests should you choose and when? Risk factors for toxicity are high dose, long duration, renal disease and tamoxifen. If you are coming to the OA July Scientific Meeting July 29th Red Hill, you will hear more about Plaquenil toxicity. As opposed to the 2011 guidelines, “real weight” is now considered a better indicator than “ideal weight” for calculating dosage for most patients. For example, for the maximum safe dose of 5.0mg/kg, the threshold dose would be 400mg/day for a patient weighing 175 pounds. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Aao plaquenil guideline The 2016 American Academy of Ophthalmology Hydroxychloroquine., AAO Guidelines for Chloroquine Screening Lupus and plaquenil side effects Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. Rx Side Effects New Plaquenil Guidelines and More.. How to Succeed in Plaquenil Screenings. American Academy of Ophthalmology Protecting Sight.. Recommendations by the AAO to limit HCQ dosing to 6.5 mg/kg of ideal body weight have been 31 revised to 5 mg/kg of actual body weight 5. Some authors recommend 6.5 mg/kg of actual 32 body weight with a cap at 400 mg per day and further adjustments for renal insufficiency 10. The Academy’s Preferred Practice Pattern® PPP guidelines detail essential characteristics of quality eye care, based on the best available scientific evidence. Dr. Rosenbaum reviewed the guidelines from the American College of Rheumatology, which are generally nonspecific regarding exactly how hydroxychloroquine should be used. He showed evidence that the guidelines from the AAO are indeed changing clinical practice.