Ocular effects of chloroquine therapy

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  1. eXtrime New Member

    Ocular effects of chloroquine therapy


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or. Along with its needed effects, chloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine Incidence not known. Anxiety; attempts at killing oneself Eighty-five percent of these patients have been taking chloroquine, but in recent years, an increasing number of patients have been treated with hydroxychloroquine. MAJOR OCULAR ADVERSE EFFECTS Corneal Deposition Corneal deposits were first described in 1958 by Hobbs and Calnan 2. These corneal deposits.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Ocular effects of chloroquine therapy

    Effects of chloroquine on viral infections an old drug., Chloroquine Side Effects Common, Severe, Long Term.

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  3. Apr 02, 2019 For Treatment of Acute Attack. Adults An initial dose of 1 g = 600 mg base followed by an additional 500 mg = 300 mg base after six to eight hours and a single dose of 500 mg = 300 mg base on each of two consecutive days. This represents a total dose of 2.5 g chloroquine phosphate or 1.5 g base in three days.

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    More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Ocular adverse reactions are photophobia, cornea verticillata, poliosis, cataract, extraocular muscle palsy, anterior uveitis, toxic maculopathy and optical neuritis. PURPOSE Bibliography review of complications due to the use of chloroquine and its derivatives. To analyze the current practice and propedeutics' evolution. Chloroquine-induced pruritus remains one of the most common side-effects in the use of chloroquine in the prophylaxis and treatment of uncomplicated malaria before the advent of artemisinin-based combination therapies.

     
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  5. Gazprom Guest

    Hydroxychloroquine Plaquenil Side Effects & Dosage for. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An ophthalmologist eye specialist often can detect changes in the retina that suggest toxicity before serious damage occurs.

    Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria
     
  6. nabihyt User

    What Is Plaquenil? - American Academy of Ophthalmology Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision.

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