SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. Can i take plaquenil for discoid lupus flare Plaquenil build up The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients. Rheumatology Oxford. 2011 May;505982-8. doi 10.1093/rheumatology/keq376. Epub 2011 Jan 18. Lupus Systemic Lupus Erythematosus or SLE Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. Systemic lupus erythematosus SLE, also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe. The seriousness of SLE can range from mild to life-threatening. There is no cure for lupus, but medical interventions and lifestyle changes can help control it. Hydroxychloroquine for systemic lupus erythematosus Systemic Lupus Erythematosus SLE CDC, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Hydroxychloroquine tablets ip 200 mg usesOsteo bi-flex triple strength and plaquenil Hydroxychloroquine is considered safe in all trimesters of pregnancy. Due to the high risk of flare in systemic lupus erythematosus when discontinuing this medication, continued Plaquenil use is advised in these patients during pregnancy. Hydroxychloroquine Plaquenil RheumTutor. Systemic lupus erythematosus - Wikipedia. A Randomized Study of the Effect of Withdrawing Hydroxychloroquine.. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. Objective To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Background. Hydroxychloroquine HCQ is an antimalarial drug that is recommended as a safe, daily prophylactic intervention for individuals with systemic lupus erythematosus SLE based on previous studies that showed an association of HCQ use with reductions in flares compared with placebo.