Im thinking a rash stays a lil & doesnt come for 10 minutes & then goes. I get facial flushing BUT when I was at the rhemy the other day, I was trying to explain to him how I get this. He said "you have it right now" But said it wasnt the ONLY show up during a FLARE because mine seems to come & go ALL the time. Spell hydroxychloroquin Hydroxychloroquine side effects diarrhea How long does it take for plaquenil hydroxychloroquine to work with rashes? Answers Follow Share 2 doctors weighed in How long does it take for plaquenil hydroxychloroquine to work with rashes? 2 doctors weighed in Dr. Bruce Rothschild. Internal Medicine - Rheumatology. I had a skin rash from plaquenil hydroxychloroquine. I was put. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Dublin - Aching joints, chronic fatigue, butterfly-shaped facial rash, hair loss, mouth ulcers, organ damage. these are just a few of the symptoms that could point to an autoimmune disorder called lupus. It’s often referred to as a woman’s disease as it affects about nine times as many women as men. I've read at least a dozen online articles to try to figure things out, and I'm even more confused after reading because some of them contradict the others! Also when im cooking, I ALWAYS get it from being in/out of the oven......... THXXXX __________________Rachel Hi Rachel, I'm no expert at all...main reason I'm replying to you is because I've wondered the same thing myself. Does plaquenil take away the butterfly rash Hydroxychloroquine User Reviews for Systemic Lupus., Plaquenil Oral Uses, Side Effects, Interactions. What are the long term side effects of plaquenil Plaqunil rash. Support Forums. How does Plaquenil work? Surprisingly, the reason for its success in lupus still remains somewhat mysterious. It has a wide variety of known effects – aspirin-like anti-inflammatory, mild immunosuppressive and mild cholesterol lowering amongst others. Perhaps an important property is that of sun-protection. Plaqunil rash -. Lupus The butterfly effect IOL. Surprising Facts About Lupus That Many People Don’t Know.. The fact that you do have a butterfly rash and are responding to Plaquenil would be a better indication that you do have lupus, though most dr.s will not give a true diagnosis without one of the more specific lupus tests being positive. You could develope abnormal test results in the future or you may not. Here you can read posts from all over the web from people who wrote about Butterfly Rash and Sjogren's Syndrome, and check the relations between Butterfly Rash and Sjogren's Syndrome. I am now taking plaquenil. Anyone on this and how well does it work. butterfly rash, etc. I tested positive for ANA but not the sjogren's antibodies. ACLE generally causes redness over the cheeks and nose. The redness is often called a “butterfly rash.” It fades over a few weeks and does not leave scarring. The rash is usually seen in people with systemic lupus who are having a flare. It can be brought on or worsened by exposure to sunlight. People with lupus must protect themselves from the sun.