It leads to fluid buildup, especially in your legs. Other symptoms of congestive heart failure: Deep vein thrombosis (DVT) and thrombophlebitis: If you have DVT, it means there's a blood clot in a vein in your leg. When that happens, it's called a pulmonary embolism, and it can be life-threatening. Chloroquine toxicity cells Chloroquine for transduction Hydroxychloroquine logp Nov 28, 2018 Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes. When the left ankle swelledup, it is the one with the worst vitiligo hyperpigment and lump, and the left side of my heart had some atrophy that my recent cardiologist could not find, though I have an irregular heart beat on the left side, off the plaquenil, my leg very nearly turned blue when it swelled and it was cold. Plaquenil and Swelling - from FDA reports Summary Swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Osteoporosis. One of the first symptoms of DVT or thrombophlebitis is one swollen leg (especially the calf), as blood pools in the area. In thrombophlebitis, also called superficial thrombophlebitis, clots form closer to the surface of the skin and aren't likely to break off. Plaquenil leg swelling Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Can't stop plaquenil? Swelling/heart palpitation Plaquenil gasHydroxychloroquine insomniaCan plaquenil cause weight lossWill i feel worse before i feel better on plaquenil Sep 13, 2019 Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Will you have Swelling with Plaquenil - eHealthMe. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Unilateral upper limb edema refers to the swelling of the soft tissues of either the right or left arm or hand. If it occurs in the upper extremity, it is usually due to problems with drainage of the blood or lymph from the arm. A deep vein thrombosis is a blood clot in one of the deep veins of the arms. The typical culprit is cancer. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. This will help reduce swelling, pain, and.