The stange thing is that these patches appear suddenly, and then disappear just as suddenly, generally in under 30 minutes. The patches appear on his face, arms, legs, and torso, even a couple on his scalp. Treatment of hydroxychloroquine retinopathy Method of action of chloroquine Does plaquenil reduce pain in osteoarthritis Is plaquenil ok with flu shot Mar 03, 2012 Nasty Skin Rash That Won't Go Away After Several Months Of Treatment? D Hello there D I'm wondering if anybody can help me, D I'm a 20 year old female. For example Plaquenil Your body then makes a chemical that causes the allergic reaction. So every time you are exposed to the allergan, the body makes the chemical very quickly as it now knows how and you get a rash, or other symptoms. They can show up and drive a person crazy for a long time only to disappear almost overnight. If the rash stays when you have been off the plaquenil it could well be from something else. Then there is the other possibility---who the heck knows. My hubby suffered with the hivey rash like yours here and there and everywhere for many months. The combination of Bendaryl and Hydrocortisone cream seems to give him some relief from the itching during the worst outbreaks, but nothing seems to work to cure it all together. This has been going on for 48 hours, and there does not seem to be any discernible trigger. While he does have excema and has had allergic reactions before, this is most unusual for him. Rash dissappears with plaquenil a month RASHES ON CHILDREN Pediatric Doctor Advise, Allergic reaction to plaquenil DailyStrength Plaquenil price ukAtarax and hydroxychloroquine suicide Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Plaquenil Side Effects Common, Severe, Long Term -. Terrible Itching on Plaquenil---PLEASE HELP.. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. The rash can be mild or severe but is not usually painful. It can be itchy if it is more like a rash than a blush and some patients even report a ‘hot’ feeling with more severe malar rashes. This type of rash tends to occur in the systemic form of the disease SLE, where other organs in the body may also be involved. 2. Hydroxychloroquine Plaquenil stimulates the pigment producing cells in the skin called melanocytes. As a result, there is both hemosiderin iron and melanin accumulation in the dermis. The exact reasons why this phenomenon happens is not clear. However, trauma and bruising may faciliate the developement of pigmentation. Jessie, plaquenil can take up to 6 months to take effect. I was told to not not try to discontinue any of my lupus meds while my medical condition was unstable. At the time, I had a sinus infection. Jessie, 3 years ago, my doctor discontinued my plaquenil ie. hydroxychloroquen and substituted it for an older anti-malerial drug named "chloroquin".