Please review the following URL and make sure that it is spelled correctly. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine sulphate with leflunomide Chloroquine treatment in huh7 cells How long does it take for plaquenil to work? I just started about 6 weeks ago, the rheum said it can take up to a year. Let me know how you are doing on it. And, you should have regular eye screenings the entire time you take the medication. While eye damage only occurs in about 1 in 5,000 people that take the drug for at least 5 years, it is important to monitor. It is crucial that you do NOT smoke while taking Plaquenil, or other antimalarial medications. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. How long does plaquenil take to work for lupus PLAQUENIL" Rheumatoid Arthritis Community - Support Group, Plaquenil Hydroxychloroquine for Lupus - LupusCorner Plaquenil increases sugar levelsPlaquenil changed your hairPlaquenil and sex drive Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Before taking this medicine. You should not use Plaquenil if you are allergic to hydroxychloroquine. Plaquenil Uses, Dosage & Side Effects -. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Hi everyone, I was just wondering how long it took for Plaquenil to start working for you? I've been on it for about a month now, and it hasn't worked for me yet, but I know that it can take up to 4 months to kick in. Hopefully that's not the case! Donald E. Thomas Jr. MD, FACR, FACP, a practicing rheumatologist in Greenbelt, Md. and author of The Lupus Encyclopedia, regularly prescribes Plaquenil to his lupus patients. “We know that people with lupus who take their Plaquenil regularly are much more likely to live a long, normal life compared with those who don’t,” he says.