Retinal changes with plaquenil

Discussion in 'Northwest Pharmacy' started by snoop, 23-Feb-2020.

  1. LenkaAOE Guest

    Retinal changes with plaquenil


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been. Hydroxychloroquine Plaquenil, Sanofi-Aventis remains widely used in the treatment of various rheumatologic disorders. A small percentage of patients exposed to hydroxychloroquine will develop irreversible, and potentially progressive, retinal toxicity for which no effective treatment exists. The changes are most often permanent, but in some cases, vision has improved. Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. Risk factors include advanced age and having pre-existing retinal disease.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Retinal changes with plaquenil

    My Take on New Ocular Screening Guidelines for Plaquenil., Retinal Physician - New Screening Guidelines for.

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  7. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

    • Hydroxychloroquine-Induced Retinal Toxicity - American..
    • Plaquenil Side Effects on Your Eyes and Vision.
    • LONGITUDINAL CHANGES IN EYES WITH HYDROXYCHLOROQUINE RETINAL..

    Over time, Plaquenil can accumulate in the retina and cause permanent irreversible damage to the center of vision. The classic retinal changes appear as a “bull’s eye” area of discoloration of the central part of the retina. Symptoms of Plaquenil toxicity are similar to other macular problems. Currently, one of the primary functional screening tests recommended for the evaluation of Plaquenil retinal toxicity is 10-2 white stimulus automated visual fields; however, research shows Asian patients benefited from 24-2 or 30-2 visual fields, given that toxicity often manifests changes beyond the macula in these patients. 9 Because spectral-domain optical coherence tomography SD-OCT is readily accessible and able to detect early structural damage prior to clinical funduscopic findings. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision.

     
  8. Mugen XenForo Moderator

    The page you are trying to reach is not available on our site. The page name may have changed, you may have happened upon a broken link, or the URL may be entered incorrectly. Why There's More to Sjogren's Syndrome The Dr. Oz Show Primary Sjogren's Syndrome Is there anybody on. - LUPUS UK Plaquenil and Depression/Anxiety - Sjogren's Syndrome Support
     
  9. passportu New Member

    RSS - Reef Medicine Series. Chloroquine Phosphate RSS Feeds Marine. There is so much misinformation out there on disease and parasite control in our hobby. I decided to meet up with veterinarian Dr. Charlie Gregory of Healthy Aquatics Marine Institute, who specifically deals with fish and corals, to set the record straight and to start off a new series on the.

    Another use for chloroquine phosphate - The Lounge MARSH - Marsh-Reef
     
  10. coding Guest

    Has anyone not been able to tolerate plaquenil. Has anyone not been able to tolerate plaquenil hydroxychloroquine and/or chloroquine - what have been your alternatives. Luckily my normal Lupus symptoms are.

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus