It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine and proguanil dose Mucinex and plaquenil Nov 15, 2015 On the other hand, high dose 1000 mg daily hydroxychloroquine can lead to retinal toxicity in less than 6 months administration. Since it is far less toxic to the retina, hydroxychloroquine has replaced chloroquine. Sep 15, 2014 Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Updated 2016 guidelines from the American Academy of Ophthalmology on screening for hydroxychloroquine retinopathy recommend a baseline fundoscopic examination followed by annual screening after 5 years with visual fields and optical coherence tomography in patients without elevated risk factors.3 Despite a good safety profile and minimal side effects, hydroxychloroquine can be toxic and even fatal when taken in excess. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Could hydroxychloroquine become toxic Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Retinal toxicity associated with chronic exposure to. Plaquenil kidney problems Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the. Hydroxychloroquine Oral Route Description and Brand.. Accidental hydroxychloroquine overdose resulting in.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Patients in earlier stages of hydroxychloroquine retinal toxicity usually do not experience symptoms, though the rare patient may note a paracentral scotoma that causes trouble with reading as well as diminished color vision. However, most patients usually notice symptoms only after scotomas have become severe. Stars. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.