The association between HCQ use and pregnancy outcomes (early spontaneous abortion, fetal death, and preterm and term live birth) was analyzed using generalized estimating equations (GEE) accounting for the occurrence of multiple pregnancies per patient. Analyses were adjusted for antiphospholipid antibody (a PL) status. 110 pregnancies (63 mostly Caucasian patients) were included, of which, in 30, HCQ was used; overall occurrence of flares was low (non-HCQ group: 5 mild (6.4%) and 2 severe (2.6%); HCQ group: 2 mild (6.7%) and no severe flares). Plaquenil liver Contraindications for chloroquine Not safe "usage of this drug during pregnancy should be avoided except when in the judgment of the physician the benefit outweighs the possible hazard. Please take note that this medication can rapidly be adsorbed by the placenta and my cause damage to the fetus's eyes. In brief Not safe. "usage of this drug during pregnancy should be avoided except when in the judgment of the physician the benefit outweighs the possible hazard. Please take note that this medication can rapidly be adsorbed by the placenta and my cause damage to the fetus's eyes. Pregnancy and Plaquenil It's not known whether Plaquenil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant before using this drug. Apart from disease flares during pregnancy, SLE patients have an increased risk of intrauterine growth restriction (OR 2.6), (pre)eclampsia (OR 3.0), and preterm birth (OR 2.4) compared to the healthy population . The HCQ group showed a trend towards lower dosage of prednisone (OR 0.2 (95% CI 0.0–1.4); Pregnancy constitutes a challenge in patients with systemic lupus erythematosus (SLE). Is plaquenil safe for pregnancy Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Is it safe to take plaquenil hydroxychloroquine while pregnant? Chloroquine phosphate ebayPlaquenil toxicity oct images Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. Hydroxychloroquine Use During Pregnancy. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. HCQ use was associated with longer pregnancy duration in the vulnerable preterm birth population, underscoring the beneficial effect of HCQ use during pregnancy. iObjective/i. To investigate the effect of hydroxychloroquine HCQ in pregnant women with systemic lupus erythematosus SLE. iMethods/i. Sunday, 01 July 2018. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. Technically, Plaquenil does not have an official pregnancy Category rating, as is common with older medications. However, most sources consider it to be a pregnancy Category C medication. In animal studies, it was shown that Plaquenil crosses the placenta and accumulates in the eyes of.