I saw a GP about it (not my usual one) and they strongly suspect it is being caused by MTX but I have just spoken to the Rheumy nurse who thinks Hydroxy is the more likely suspect or it may be an autoimmune response so now I have to withhold all rheumy meds. It seems to improve when I am on steroids but only at higher doses. Thanks, Tamara I am on all sorts of meds including MTX and Hydroxy. Teva-chloroquine phosphate How long for chloroquine to work malaria Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. And their welt rashes look exactly like the welts I had all over from this reaction. I have never had lupus rash other than the Malar rash on my face and upper chest area, and rash in my scalp. the only way to be sure is to either biopsy the rash or to restart the plaquenil. I wouldn't restart the plaquenil with the rash you have, I would. Skin rash or itching; or; hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? I can't face the GP again, as I am sure I am one of the "heart-sink" patients! I have recently developed an itchy rash which only affects my cheeks and eyebrows and haven't a clue what's causing it, so I hope you get some helpful replies that might help me too! What does a plaquenil rash look like Rheumatoid arthritis rash Causes, symptoms, and images, Allergic reaction to Plaquenil Lupus Forums at The Lupus. Does plaquenil help raynaud's SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil Hydroxychloroquine Side effects, Images, Uses.. Common and Rare Side Effects for Plaquenil Oral. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells but potentially serious eye toxicity can occur. I've been on Plaquenil for 6 weeks. I developed a red, raised, welt rash that looked like zebra stripes after being in the sun for 10 minutes. It went away within 30 minutes but then my joints all flared up the next few days. Check with your doctor! Hydroxychloroquine sulfate Images. What does Hydroxychloroquine sulfate look like? Note Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Multi ingredient medications may also be listed when applicable.