I know its a supposed small risk, but thanks to Google I've uncovered some horror stories about vision issues after just 8mo-1yr and people swearing it is actually not uncommon. I've had the worst flare of my life over late summer, I've had 3 early miscarriages in 1.5 years, I'm almost always in some type of achy state or dead tired. Potential side effects and very real risks make the medication seem ridiculously dangerous. I'm not as familiar with MCTD but what I do know is that is can be just as dangerous as SLE. Is the vision loss something that will stop if the medication is stopped? Hydroxychloroquine can it shrink spleen Retinal damage plaquenil Of all the drugs I've had to take for lupus, plaquenil is probably the most mellow. It is my understanding that if it affects your eyes, it's a slow onset type thing, so if you're having your eyes checked regularly every 6mos, you will be fine. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil takes quite a long time to get to its peak effectiveness depending on what you read, anywhere from 3 months to a year. Unless you are having significant side effects, try to give it at least 6 months before you decide it doesn't work for you. Your external symptoms are a sign that something very wrong is going on inside you. Why in the world would anyone choose to poison themselves? You have a choice to make between letting your disease run rampant and continue to damage your body until it can no longer fight back or using one of the few weapons you have at your disposal to slow it down. Unfortunately, you have to roll the dice and decide which risk you'd rather take. How long is plaquenil good Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Hydroxychloroquine wikiRa plaquenil success rates Reviews and ratings for plaquenil when used in the treatment of rheumatoid arthritis. 58 reviews submitted. it has been good for me, but the generic form of it caused me problems, so I have to take the brand name. It's been around 2 years now and I'm glad to say all side effects are long gone. So is my pain for the most part. Plaquenil User Reviews for Rheumatoid Arthritis at. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. How long taking Plaquenil before side effects DailyStrength. I know I've asked this question before, but with so many new people and so much time that's passed, I thought I'd ask again. How long did it take for Plaquenil to become effective for you? Meaning, when did you start to feel some relief from your lupus symptoms after you started taking. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs.