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The dose of azithromycin Zithromax® that your healthcare provider prescribes will vary dependingThe recommended dosage of azithromycin for the treatment of sexually transmitted diseases STD is 1 gram 1000 mg to 2 grams 2000 mg given one time only. Azithromycin is used to treat a wide variety of bacterial infections. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. This medication will not work for viral infections (such as common cold, flu). Read the Patient Information Leaflet if available from your pharmacist before you start taking azithromycin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily with or without food. You may take this medication with food if stomach upset occurs. The dosage is based on your medical condition and response to treatment. I was prescribed 1000 mg of Azithromycin for a suspected ureaplasma infection. 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