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The presence of Clavulanic acid in Augmentin protects Amoxicillin against the destructive action of beta-lactamase and increases the antibacterial activity of this medication. As most penicillins, Amoxicillin is destroyed by beta-lactamase which has high resistance to the action of this medication. Augmentin actively inhibits the development of gram-positive aerobe and anaerobe, gram-negative aerobic and anaerobic microorganisms, Chlamydia pneumoniae, Chlamydia psittaci, Chlamydia spp, and many causative agents of the infection. In case of the monotherapy of the bacterial diseases, Amoxicillin is effective only if a causative agent of the infection is well known. The spectrum of the pharmacological activity of Augmentin is conditioned by two active ingredients but the mechanism of the action is mainly conditioned by the bactericidal effect of Amoxicillin. Augmentin destroys the cellular walls of bacteria and neutralizes the possibility pf their development and growth. 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