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While twice-daily dosing is effective and can maintain a reduction in blood pressure throughout the day, some patients, especially when lower doses are used, may experience a modest rise in blood pressure toward the end of the 12-hour dosing interval. "I just discovered Propranolol (Inderal) 3 days ago and it has already changed my life. My fear is almost gone now because I know I won't blush or get nervous or start having a panic attack and this allows me to do things i've always wanted to with no fear! " Read more positive discussions I can live with the side effects and must, since it's been the only anti-hypertensive that works on me, Previous to that, I was on Inderal and while on that developed CHF and cataracts. I've read that Inderal has been known to contribute to them. I am going to talk to my doctor today to see about switching blood pressure meds. I notice that Inderal causes me to have shortness of breath. 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