Propranolol is prescribed to treat a number of different conditions. If you are unsure why you are taking it, speak with your doctor. The most common side-effects are feeling tired, cold hands and feet, disturbed sleep, and stomach upset. Propranolol belongs to the group of medicines known as beta-blockers. It is a medicine which is used to treat several different medical conditions. Propranolol slows down the activity of your heart by stopping messages sent by some nerves to your heart. It does this by blocking tiny areas (called beta-adrenergic receptors) where the messages are received by your heart. 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On average, people receiving quetiapine scored higher (better) than people treated with typical antipsychotic drugs. This finding is based on data of very limited quality. In a 2013 comparison of 15 antipsychotics in effectiveness in treating schizophrenia, quetiapine demonstrated standard effectiveness. On average, people receiving quetiapine scored lower (better) than people treated with typical antipsychotic drugs. It was 13-16% more effective than ziprasidone, chlorpromazine, and asenapine and approximately as effective as haloperidol and aripiprazole. There is tentative evidence of the benefit of quetiapine versus placebo in schizophrenia; however, definitive conclusions are not possible due to the high rate of attrition in trials (greater than 50%) and the lack of data on economic outcomes, social functioning, or quality of life. A Cochrane review comparing quetiapine to other atypical antipsychotic agents tentatively concluded that it may be less efficacious than olanzapine and risperidone; produce fewer movement related side effects than paliperidone, aripiprazole, ziprasidone, risperidone and olanzapine; and produce weight gain similar to risperidone, clozapine and aripiprazole. A 2013 study compared 15 antipsychotic drugs in treating schizophrenia. Risperidone was ranked fourth, 11% more effective than paliperidone (fifth), 20-23% more effective than haloperidol, quetiapine, and aripiprazole, and 36% less effective than clozapine (first). Studies evaluating the utility of risperidone by mouth for maintenance therapy have reached varying conclusions. A 2012 systematic review concluded that evidence is strong that risperidone is more effective than all first-generation antipsychotics other than haloperidol, but that evidence directly supporting its superiority to placebo is equivocal. 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