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Sildenafil action

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  1. spb-tuning New Member

    Sildenafil action


    Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a child's condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily. If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). cheap levitra pills uk However, patient may take drug 30 minutes to 4 hours before sexual activity. as a single dose, p.r.n., 1 hour before sexual activity. Based on effectiveness and tolerance by patient, may increase dose to maximum single dose of 100 mg or decrease dose to 25 mg. A maximum recommended dosing frequency is once daily. Erectile action: Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cyclic guanosine monophosphate (c GMP) in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of c GMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Absorption: Rapidly absorbed after oral administration. A high-fat meal delays the rate of absorption by about 1 hour and reduces peak levels by one-third.

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    The Biological Action of Sildenafil CitrateViagra™. of sildenafil citrate as an antianginal drugas coronary tissues use principally the pde-3 type receptors,see. buy kamagra online london See risks & benefits. Find a survey of men with ED who have taken VIAGRA® sildenafil citrate versus other Rx. Help eligible patients save on prescriptions. Sildenafil Action CanadianPharmacyOnline. Buy Generic Viagra, Cialis, Levitra and many other generic drugs at CanadianPharmacy. Lowest prices for Generic and Brand drugs. Bonus 10 free pills, discounts and FREE SHIPPING. Cheapest drugs online - buy and save money.

    Links to other sites are provided as a convenience to the viewer. Pfizer accepts no responsibility for the content of linked sites. This website is neither owned nor controlled by Pfizer. Pfizer does not endorse and is not responsible for the content or services of this site. Continue You are now leaving to enter a website neither owned nor operated by Pfizer. Links to all outside sites are provided as a resource to our visitors and do not imply an endorsement or recommendation of a particular physician by Pfizer, nor an endorsement of any Pfizer product by a telehealth provider or any physician. Pfizer accepts no responsibility or liability for the content or services of other websites. Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, sildenafil helps to maintain an erection after the penis is stroked.

    Sildenafil action

    How Long Does Viagra Last Effects, in Your System, More, Onset of Action VIAGRA® sildenafil citrate Safety Info - PfizerPro

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  6. Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water and a molecular weight of 666.7. REVATIO sildenafil Tablets REVATIO is formulated as white, film-coated round tablets for oral administration.

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    The following diagram shows how an erection is mediated and how sildenafil acts in the body. Nitric Oxide NO is released with sexual stimulation from nerve. dapoxetine india online Sildenafil and/or N-desmethylsildenafil, its major active metabolite, may be quantified in plasma, serum, or whole blood to assess pharmacokinetic status in those receiving the drug therapeutically, to confirm the diagnosis in potential poisoning victims, or to assist in the forensic investigation in a case of fatal overdose. Mechanism of action What is sildenafil, and how does it work mechanism of action? Viagra sildenafil is an oral drug that is used for treating impotence or erectile disfunction, ED, the inability to attain or maintain a penile erection.

     
  7. web-maniac Guest

    The following information is NOT intended to endorse drugs or recommend therapy. Very disappointing""Having tried 10mg which started to work I tried the 20mg. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."I started out with 20 mg but it worked to well. Took over 90 minutes before it kicked in and started getting aroused . I received a sample of 20mg levitra x10 and wow, I'm switching. Had hard erections on and off all day and the next. Have recently tried Levitra professional and hardly worked at all yet they say this an improved version but did nothing for me at all. I am 72 and going 2-4 times a week""I'm 64 and have been taking viagra for several years. very happy.""Had tried Levitra 20mg but only got semi hard and not solid erection and could not come at all. Tried intercourse 5 times but each time lost my erection after a few minutes so very disappointed Apparently they now have a new more recent and improved Levitra called Levitra professional so will try that and see if any better""I used 10mg Levitra for the first time. Certainly fuller and wider but not longer but still couldn't come. Tiny bit of face flushing but did have 1 large glass of white wine to relax before initiating anything. Think if I had taken 20 mg it would have done the trick as 10mg too weak for me and much better than viagra or Cialis. Will definitely use again but 20mg next time""Experience is generally very positive. Levitra User Reviews for Erectile Dysfunction at suhagra 50 buywhere can i order synthroid How long does Levitra last DB00862 - Vardenafil - DrugBank
     
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