side effect of tamoxifen is blood clots, including deep vein thrombosis (DVT) and pulmonary embolus. In some cases, health care professionals may use the trade name Nolvadex when referring to the generic drug name tamoxifen. This medication is classified as an "anti-estrogen." (For more detail, see "How this drug works" section below). You should seek emergency help and notify your health care provider immediately if you develop sudden chest pain and shortness of breath. Notify your health care provider within 24 hours if you notice that one leg is swollen, red, painful and/or warm to touch and the other is not. A side effect of tamoxifen can be the development of uterine cancer. Women who have not had a hysterectomy should have regular pap smears and gyn examinations. Abnormal vaginal bleeding should be reported to your health care provider. clonidine tab If you have been prescribed tamoxifen for breast cancer, you've likely heard that it can interact with some other medications. Since these interactions involve commonly used drugs and include over-the-counter and nutritional supplements, this is very important. In addition, you will likely be taking the medication for at least 5 to 10 years, making an awareness of possible interactions not just a momentary concern. It's been thought that there are some people who, due to genetic differences, may not benefit from the usual dose of the drug, but more recent research suggests these women do just as well with treatment. Tamoxifen is broken down into endoxifen by the cytochrome P450 enzyme CYP2D6. (There are also other enzymes such as CYP3A4 and others, but CYP2D6 is likely most significant). Anything that reduces the activity of this enzyme (CYP2D6) can result in a reduced amount of the active metabolite, and hence, less benefit. Reduced activity of the enzyme may occur if you are taking some other medications or if you have particular genetic variations that make the enzyme less active. Prednisone vomiting What Tamoxifen Is Used For Tamoxifen may be given as adjuvant therapy treatment after successful surgery in women or men with lymph node negative or lymph node positive breast cancer. Cancers with positive estrogen and progesterone receptors are more likely to benefit from tamoxifen. ciprofloxacino indicaciones What medications may interact with tamoxifen, what is the mechanism, and what drugs may be used instead? How can genetics influence tamoxifenTamoxifen is used for both women and men who have metastatic breast cancer that is estrogen receptor positive and who are not resistant to the drug. Tamoxifen, sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men. Tamoxifen is a drug called an estrogen receptor antagonist, which works by blocking the receptor so that estrogen can’t work its usual effects within the body. Estrogen is an important hormone in the female body and plays a big role in some types of breast cancer. As a result, tamoxifen is commonly used to prevent breast cancer from appearing or coming back in women who are at a high risk of or have a history of breast cancer. This is not the only way that tamoxifen can be used, however, and there are several alternative ways that this drug can be used to offer a benefit. The following information goes into more detail about alternative uses of the medication and how it can be used. Some individuals that experience premature puberty may notice symptoms of Mc Cune-Albright syndrome, such as bone disfiguration and skin discoloration. Tamoxifen can be used to decrease the rate of bone maturation and alter the predicted adult height, which is usually lower in those with premature puberty. Tamoxifen is a nonsteroidal agent which is used in both men and women to treat breast cancer. This medicine is not recommended for use in pregnant women. It is advised that you discuss all the risks and benefits with your doctor before taking this medicine. This medicine is not recommended for use in pregnant women due to the potential for serious adverse effects on the unborn baby. It should only be used in life-threatening conditions where the potential benefits outweigh the risks. We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Tamoxifen what is it used for Tamoxifen Uses, Side Effects, and More, What Can You and Can't You Take While Using Tamoxifen Nolvadex testosterone booster Metoprolol overdose amount Tamoxifen is a nonsteroidal agent which is used in both men and women to treat breast cancer. It is also used in women to prevent breast cancer. This medicine is not recommended for use in pregnant women. It is advised that you discuss all the risks and benefits with your doctor before taking this medicine. Tamoxifen - Uses, Dosage, Side Effects, Composition. - Practo Tamoxifen - Wikipedia Tamoxifen Side Effects, Dosage, Uses, and More It is used to treat breast cancer and to prevent new breast cancer. have heard tamoxifen called little chemo and can be very effective if you don't have access to. xenical priceline Tamoxifen is a well-known drug discovered by what is now AstraZeneca. It was originally screened in a development program centered on the introduction of new contraceptive agents. Although it proved effective in rats, it was not a useful drug for control of fertility in women; it actually induced ovulation. Tamoxifen may also be used as a preventive therapy in women who have an elevated risk of developing breast cancer. In this setting, it can reduce a women's risk of developing breast cancer by half. The most common dosage is 20 mg daily for 5 to 10 years.