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The mediation is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. Zoloft is a selective serotonin reuptake inhibitor (SSRI). SSRIs are the most commonly prescribed type of antidepressants, and they work by increasing levels of serotonin in the brain. They are also sometimes prescribed to treat anxiety and other conditions. If you have bipolar disorder and take an SSRI, you may be at risk for triggering a manic episode if you are not also taking a mood stabilizer. Talk to your doctor about your specific symptoms, other health concerns, and other medications you take so they can make the best recommendation for your condition and symptoms. I am grateful to the creators of this amazing medicine as it ridded me of many problems in my personal life. I was simply unable to have normal sexual relationship with women. 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